C-Trap® Optical Tweezers is a dynamic single-molecule microscope to allow simultaneous manipulation and visualization of single-molecule interactions in real time. Faculty Incharge: Dr. Soumit Sankar Manda
Author: Sai Kumar GA
Isothermal Titration Calorimetry (Malvern MicroCal ITC)
ITC measures heat released or absorbed during biochemical binding events to calculate binding affinity (K D ), stoichiometry (n), enthalpy (ΔH) and entropy (ΔS) in a single experiment. Faculty Incharge: Dr. Soumit Sankar Mandal
Bio Layer Interferometry – Octet® R4 Protein Analysis System
The 4-channel Octet® R4 instrument can be used for a wide range of analyses including kinetic analysis, titer of IgG and other proteins, reagent qualification, immunoassay development, bioprocess development, quality analysis, crude antibody screening, epitope binning/mapping, ligand binding assays, and small molecule analysis, elucidating cell signaling mechanisms, and infectious disease monitoring. Faculty Incharge: Dr. Soumit… Continue reading Bio Layer Interferometry – Octet® R4 Protein Analysis System
Cyclic Voltammetry – Biologic – SP 200 Potentiostat
For study various electrochemistry applications like Corrosion / Coating, Electrolysis Fundamental and analytical electrochemistry research, fuel cell and batteries, Sensors Faculty Incharge: Dr. Pankaj Kumar Koli
Benchtop NMR : Spinsolve 80 Ultra – Carbon – Magritek
This Benchtop NMR is capable of determining the molecular structure based on the chemical environment of the magnetic nuclei like 1H, 13C, 19F, T1, T2, HMBC, HSQC, DEPT, COSY etc. Faculty Incharge: Dr. Gopinath Purushothaman
Single Crystal XRD: Bruker D8- Venture Diffractometer Photon III – Duo
Single-crystal X-ray diffraction is most commonly used for precise determination of a unit cell, including cell dimensions and positions of atoms within the lattice. Bond-lengths and angles are directly related to the atomic positions. Both Mo and Cu sources are available for measurement. Faculty Incharge: Dr. Sudipta Roy
GCMS with HSS (Agilent)
For analysis of low molecular weight volatile and semi-volatile organic and inorganic compounds. EI and CI ionization sources with GC-FID (G3540A-Agilent 8890), GC-MSD (7078B) detectors and HSS 7697A (G4556A). Head Space provides an inert sample pathway for superior gas chromatography performance without analyte degradation or loss. Faculty In charge: Dr. Sudipta Roy
Fluorescence Correlation Spectrometer (FCS)
Fluorescence Correlation Spectrometer (FCS) is a diffusion-based single-molecule technique. In this technique, spontaneous fluorescence fluctuation is collected from very few molecules as they diffuse in and out of a tiny observation volume (~1 fL) over time. The fluorescence fluctuations are correlated to obtaining dynamic information contained in the fluctuation. By analyzing the correlation curve with suitable models, one can quantitatively measure diffusion coefficient, viscosity, chemical kinetics, size, etc.
Pulse Field Electrophoresis System Make: Bio-Rad Model: 1703672 CHEF Mapper XA Chiller System
PFGE resolves DNA by alternating the electrical field between spatially distinct pairs of electrodes. This technique results in the separation of DNA fragments of up to ~10 Mb by their reorientation and movement at different speeds through the pores of an agarose gel. Contact: Dr. Vijayalakshmi V Subramanian
Laboratory Glassware Washer Make: Lancer Model: 1300LX
Automated machine involved in cleaning glasswares with assistance of pre-mixed mild acid and detergents and injection ports for cleaning with demineralized water. Contact: Dr. Vijayalakshmi V Subramanian
